This Article From Issue
March-April 2022
Volume 110, Number 2
Page 76
The sequence of each variant is drawn as a path, colored by open reading frames (ORFs) and genes S, E, M, and N (which also contains ORF9b and ORF9c). The length of the path is proportional to the size of the genome. The path curvature is proportional to the repeat content, and the direction of curvature relates to the genomic base composition—specifically, it indicates whether the guanine-cytosine content is lower or higher than average.
Mutations found in at least 75 percent of a with mutation single variant’s sequences are shown at their position in the genome and colored by gene.
Omicron has a large number of unique mutations in ORF1a and in the spike protein gene.
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Data source: NIH/NCBI Virus, longest complete sequence for each variant; outbreak.info
Infographic by Martin Krzywinski.
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